Sialochemistry in evaluating bromhexine treatment of Sjogren's syndrome.

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Primary Sjogrens Syndrome in a Child

Sjögren syndrome is uncommon in children and occurs most often in association with autoimmune diseases (secondary Sjögren syndrome). We describe the clinical and biological features of a 7-year-old girl with primary Sjögren syndrome revealed by recurrent parotiditis. CASE REPORT A 7-year-old girl was referred for investigation of multiple episodes of parotid swelling since age 4 years, withou...

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3431 Conjunctiva immunopathology in primary sjogrens syndrome (1° S.S.)

Aim: To evaluate the histological changes and immune response of conjuctiva in patients (pts) with lo S.S. Materials and Methods: We studied conjunctiial biopsies from 15 pts with I0 S.S. and 2 normal controls using 1) paraflfn section screening for the quality of conjunctival epithelium (CE), the number of goblet cells (GC) and the degree of inflammation, 2) Mo-abs and Pabs to: Tlymphocytes, T...

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Sjogrens syndrome--the non-apoptotic model of glandular hypofunction.

The ‘classical’ model to explain glandular hypofunction in Sjögrens syndrome (SS) is tissue loss secondary to immune attack mediated by a combination of apoptosis and cytotoxic cell death (reviewed recently by Ramos-Casals and Font [1]). In this model, the process of glandular destruction is made self-sustaining by the continued production of novel ‘self ’ antigens, secondary to apoptotic bleb ...

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Sialometry and sialochemistry: diagnostic tools for Sjögren's syndrome.

BACKGROUND The common occurrence of xerostomia in Sjögren's syndrome (SS) as well as the easy accessibility of saliva supports the use of sialometry and sialochemistry in the diagnosis of SS. Collection and analysis of whole saliva (oral fluid) is currently the routine technique for sialometry, despite the fact that it is rather inaccurate and impure. OBJECTIVE To assess the value of glandula...

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ژورنال

عنوان ژورنال: BMJ

سال: 1979

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.6194.833